“… Fe2+ ( 10–100 μmol/L) dose-dependently increased the expression and nuclear translocation of NF-κB … blocked by co-treatment with curcumin (20 μmol/L) or the NF-κB inhibitor PDTC (10 μmol/L).Conclusion:Curcumin effectively attenuates brain edema … pathway and subsequently the expression of AQP4 and AQP9.”