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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Three of the nine cleavage reactions occur between a phenylalanine or a tyrosine and a proline.”
HIV protease inhibitors: antiretroviral agents with anti-inflammatory, anti-angiogenic and anti-tumour activity.“In the presence of proline , small additional increases of the EGF effect on DNA synthesis were stimulated by phenylalanine and tyrosine.”
Proline is required for the stimulation of DNA synthesis in hepatocyte cultures by EGF“The dipeptide phenylalanine + proline induced a measurable imprinting in the liver cells, and chain length increase, especially terminal coupling with tyrosine enhanced the imprinting potential enormously.”
“The rate constants for tyrosine oxidation decreased by 125-fold with three added prolines residues between tyrosine and the oxidant.”
Shallow Distance Dependence for Proton-Coupled Tyrosine Oxidation in Oligoproline Peptides.“Steric interactions between the atoms of the proline ring and a tyrosine ring (Tyr166) on one side of the proline prevent the ring from adopting the up pucker (χ1 is approximately −30°), while the side chain of a nearby alanine (Ala171) forbids the down pucker (χ1 is approximately +30°).”
“Hydrophobic contacts between the rings of tyrosine 1 and proline 3 may enhance the stability of the N-terminal segment.”
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