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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“At both sites, cleavage occurs between proline and an O-linked glycosylated threonine , and deglycosylation of fXII prevents cleavage by CpaA. Consistent with this, mutant fXII (fXII-Thr309Lys) from patients with hereditary angioedema type III (HAEIII) is protected from CpaA inactivation.”
CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII“It is likely that resistance to beta-elimination is due to very close proximity of proline to the glycosylated serine or threonine residues.”
“Our data suggest strongly that the proline to threonine substitution may alter the protein folding or decrease the thermodynamic stability or solubility of the protein.”
“Whole-body glycine, proline , serine and cystine concentrations decreased (P < 0.05) as Thr was increased in the diet.”
Maintenance threonine requirement and efficiency of its use for accretion of whole-body threonine and protein in young chicks.“Analysis of the simulations shows that Ser or Thr can significantly modulate the deformation of the Pro.”
Ser and Thr residues modulate the conformation of pro-kinked transmembrane alpha-helices.
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