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The Journal of clinical investigation • 1971 | View Paper
“Turnover with sarcosine and the limiting rate of the reductive half-reaction with L-proline at pH 8.0 are, however, nearly 2 orders of magnitude slower than that with with wild-type MSOX.”
“The largest degree of stabilization is achieved with 6m sarcosine , which increases the denaturation temperatures of RNase S and S pro by 24.6 and 17.4 °C, respectively, at pH 5 and protects both proteins against tryptic cleavage.”