Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Proline and Bismuth Subsalicylate

Research Papers that Mention the Interaction

In vitro experiments … that severe acidic stress (pH 1.75) induced the processing of pro –IL-1β into its 18-kDa mature form (p18–IL-1β), which was different from the caspase-1–processed 17-kDa form (p17–IL-1β), in human THP-1 macrophages and primary murine macrophages.
The Journal of Immunology  •  2019  |  View Paper
In response to acid stress , the increased levels of intracellular glutamic acid, alanine, cysteine, and proline contributed to the maintenance of intracellular pH homeostasis via decarboxylation and alkaline neutralization.
Environmental research  •  2021  |  View Paper
Metabolic processes like pentose phosphate pathway, fatty acid biosynthesis, cysteine and methionine metabolism and synthesis of arginine and proline were remodeled during acid stress.
Scientific Reports  •  2018  |  View Paper
The results showed that enhancement of Cu stress (100 to 300 mg kg−1) resulted in a decrease in various compatible solutes such as proline , total soluble sugars, and total protein content, and increase in the level of malondialdehyde (MDA), latter of which is the indicator of oxidative stress.
Environmental Science and Pollution Research  •  2018  |  View Paper
We hypothesized that addition of proline protected the cells from acid stress by combating acid-induced oxidative stress.
Journal of bioscience and bioengineering  •  2015  |  View Paper
Moreover proline accumulation in Cu stress plant seems to provide additional defense against the oxidative stress.
Plant physiology and biochemistry : PPB  •  2012  |  View Paper
A large body of data suggests a positive correlation between proline accumulation and plant stress.
Plant signaling & behavior  •  2012  |  View Paper