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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Proline
Research Papers that Mention the Interaction
“In vitro experiments … that severe acidic stress (pH 1.75) induced the processing of pro –IL-1β into its 18-kDa mature form (p18–IL-1β), which was different from the caspase-1–processed 17-kDa form (p17–IL-1β), in human THP-1 macrophages and primary murine macrophages.”
Inflammasome-Independent and Atypical Processing of IL-1β Contributes to Acid Aspiration–Induced Acute Lung Injury“In response to acid stress , the increased levels of intracellular glutamic acid, alanine, cysteine, and proline contributed to the maintenance of intracellular pH homeostasis via decarboxylation and alkaline neutralization.”
The adaptation mechanisms of Acidithiobacillus caldus CCTCC M 2018054 to extreme acid stress: Bioleaching performance, physiology, and transcriptomics.“Metabolic processes like pentose phosphate pathway, fatty acid biosynthesis, cysteine and methionine metabolism and synthesis of arginine and proline were remodeled during acid stress.”
“The results showed that enhancement of Cu stress (100 to 300 mg kg−1) resulted in a decrease in various compatible solutes such as proline , total soluble sugars, and total protein content, and increase in the level of malondialdehyde (MDA), latter of which is the indicator of oxidative stress.”
“We hypothesized that addition of proline protected the cells from acid stress by combating acid-induced oxidative stress.”
“Moreover proline accumulation in Cu stress plant seems to provide additional defense against the oxidative stress.”
“A large body of data suggests a positive correlation between proline accumulation and plant stress.”
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