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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progestins
drug:
Lamotrigine
Research Papers that Mention the Interaction
“All progestagens as well as 11-deoxycorticosterone and corticosterone increased 100–200% with increasing concentrations of LAM suggesting a selective inhibitory effect of LAM on CYP17A1, in particular on the lyase reaction.”
The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro†“There is preliminary evidence that lamotrigine induces the metabolism of a progestin , levonorgestrel.”
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