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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Progestins and Felbamate

supplement:

Progestins

Research Papers that Mention the Interaction

Phenobarbital (phenobarbitone), phenytoin, carbamazepine, oxcarbazepine, felbamate and topiramate have been shown to increase the metabolism of ethinylestradiol and progestogens.
CNS drugs  •  2002  |  View Paper
Although not yet examined in vitro, felbamate appears to induce the activity of CYP3A4, which would account for it reducing plasma concentrations of carbamazepine or the progestin gestodene.
Clinical pharmacokinetics  •  1997  |  View Paper