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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progestins
drug:
Drospirenone
Research Papers that Mention the Interaction
“Mixtures of DRS and P4, as well as of DRS and EE2 showed additive progestogenic and androgenic activities.”
Activity of binary mixtures of drospirenone with progesterone and 17α-ethinylestradiol in vitro and in vivo.“In the case of the other five reductases, gestagens had remarkably stronger inhibitory effects at a concentration of 25 μM (progesterone: 66-88% inhibition; drospirenone : 26-87% inhibition) in comparison to estrogens (estradiol: 17-51% inhibition; ethinylestradiol: 14-79% inhibition) and androgens (14-78% inhibition).”
“Several studies have shown that drospirenone , a progestin available in certain OCs, minimizes the potential negative effect the progestin has on acne.”
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