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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Progestins and Arachidonate

supplement:

Progestins

supplement:

Arachidonate

Research Papers that Mention the Interaction

Arachidonate and other long-chain fatty acids … specific binding of estrogen ([3H]R2858), progestin ([3H]R5020), androgen ([3H]R1881) and glucocorticoid ([3H]dexamethasone) to the respective receptors in brain (neonatal cerebral cortex … area, HPOA), uterus and prostate, with the exception of the potentiating effect on the brain estrogen receptors.
In addition, arachidonate lowered dose-dependently the peak of labelled progestin or estrogen binding to the 8S receptor proteins, which were collected from fractions in the 8S region of the cytosols from intact or diethylstibestrol-primed rat uteri.
Journal of steroid biochemistry  •  1989  |  View Paper