Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Progesterone and Vitamin E

supplement:

Progesterone

supplement:

Vitamin E

Research Papers that Mention the Interaction

A hypothesis involving the possible formation of a chemical complex between progesterone and α-tocopherol is offered to explain the mechanism of α-tocopherol action on oxidative phosphorylation inhibited by progesterone.
Binding of progesterone to rat liver mitochondria was slightly increased by α-tocopherol.
Inhibition by progesterone of NADH oxidation was also reversed by α-tocopherol in sonic particles.
Tocopherol acetate reversed the inhibitory effect of progesterone on succinate oxidation much more weakly than α-tocopherol.
Journal of steroid biochemistry  •  1975  |  View Paper