Possible Interaction: Progesterone and Vitamin D

“The transverse mean … was higher after CC (13.6 +/- 0.5 mIU/ml) than after placebo (8.….3 mIU/ml; P less than 0.001), and luteal phase length was increased from 13.5 +/- 0.5 to 16.….4 days (P less than 0.001) by administration of CC.”

“Moreover, vitamin D might influence steroidogenesis of sex hormones (estradiol and progesterone ) in healthy women and high 25(OH)D levels might be associated with endometriosis.”

“Modest benefits were attributed to minocycline and Sygen (without statistical significance), and some benefits were obtained with erythropoietin and progesterone plus vitamin D in neurological outcome.”

“The fragmentation rate of embryos categorized as "top quality" in D3 increased proportionately to increases in progesterone levels (12.23%).”

“Those who received progesterone and vitamin D had significantly higher motor powers and sensory function after 6 months of therapy.”

“Downregulation of IL-6 expression by estrogen and progesterone was potentiated when vitamin D was included.”

“ConclusionsHigher levels of vitamin D may reduce progesterone and estradiol, providing a potential mechanism for reduction in breast cancer risk from increased vitamin D exposure in young women.”

“There were significant positive correlations between FF levels of 25(OH)D with TAC, estradiol and progesterone concentrations, SOD, GPx, and CAT activities.”

“Conclusion: The results showed that recovery rate in patients with severe brain trauma in the group receiving progesterone and vitamin D together was significantly higher than that of progesterone group, which was in turn higher than that of placebo group.”

“Cortisol, oestradiol and progesterone displaced bound labelled vitamin D3 to a lesser extent, whereas 5 beta-dihydrotestosterone, lanosterol and diosgenin were ineffective.”