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Last Updated: 8 months ago

Possible Interaction: Progesterone and Tyrosine





Research Papers that Mention the Interaction

Although the complete signaling pathway is not clear, progesterone activates phospholipase C and protein kinases and enhances tyrosine phosphorylation.
The Journal of Physiological Sciences  •  2015  |  View Paper
Both A23187 and progesterone markedly inhibited tyrosine phosphorylation of sperm STAT 4.
Fertility and sterility  •  2001  |  View Paper
However, after incubation for 5 h, progesterone was able to enhance the tyrosine phosphorylation of a 95 kD sperm protein, which is phosphorylated progressively during capacitation in well-defined culture media.
International journal of andrology  •  1996  |  View Paper
These experiments revealed a selective increase in the tyrosine phosphorylation of a 94-kilodalton phosphoprotein in the presence of progesterone.
Endocrinology  •  1993  |  View Paper
The results showed that the three concentrations (0.02 mmol/L, 0.2 mmol/L and 2mmol/L) of tyrosine inhibited progesterone secretion by trophoblast cells in vitro.
While progesterone secretion was suppressed by tyrosine , hCG secretion was unchanged.
Sheng li xue bao : [Acta physiologica Sinica]  •  1989  |  View Paper
Site-directed mutagenesis indicated that a tyrosine residue at position 464 of WT1 increased the 17α-hydroxylation of progesterone compared with an asparagine residue at that position of WT2.
Journal of animal science  •  2013  |  View Paper
tyrosine phosphorylation … by progesterone at 10(-5) M. These results indicate that progesterone is implicated in insulin resistance during pregnancy by inhibiting the PI 3-kinase pathway … and 2) distal to Akt and 3) by suppressing the PI 3-kinase-independent pathway of TC10 activation by affecting Cbl phosphorylation.
American journal of physiology. Endocrinology and metabolism  •  2010  |  View Paper
In contrast, progesterone significantly increased the levels of PP2A phosphorylated in tyrosine 307 in the hippocampus and the cerebellum and significantly decreased the levels of PTEN phosphorylated in serine 380 in the hypothalamus and in the hippocampus compared with control values.
Journal of neuroscience research  •  2010  |  View Paper
Tyrosine 170 on day 6-10 of gestation significantly decreased the concentration of serum progesterone in early pregnant mice.
Yao xue xue bao = Acta pharmaceutica Sinica  •  1997  |  View Paper
hCG, cAMP and progesterone all could significantly increase the content of tyrosine in the suspensions, suggesting the release of "endogenous tyrosine".
Sheng li xue bao : [Acta physiologica Sinica]  •  1989  |  View Paper
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