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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
supplement:
Trypsin
Research Papers that Mention the Interaction
“It was found that progesterone has increased cell resistance to trypsin digestion and increased cell attachment to extracellular matrix proteins, especially laminin and fibronectin.”
Effect of progesterone on the invasive properties and tumor growth of progesterone receptor-transfected breast cancer cells MDA-MB-231.“These results show that trypsin and chymotrypsin inhibitors are effective in blocking the acrosome reaction induced by progesterone in canine; in addition, they suggest the participation of respective proteases in the AR process in this species.”
Trypsin and chymotrypsin are involved in the progesterone-induced acrosome reaction in canine spermatozoa.“On the other hand, both 17β‐estradiol and progesterone dose‐dependently enhanced the contractile response to trypsin.”
“In addition, a sperm trypsin like protease may be part of the mechanism by which progesterone stimulates AR.”
“ Progesterone binding activity was directly proportional to the sample concentration, was significantly reduced by trypsin digestion, and was pH-dependent and temperature-sensitive.”
“ Trypsin pretreatment of microsomes inhibited the esterification of both sterols and a similar dose-dependent inhibition was produced by addition of progesterone and several androgens.”
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