Discover Supplement-Drug Interactions
The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided…
8 months ago
Possible Interaction: Progesterone and Tretinoin
Research Papers that Mention the Interaction
also induced the de novo synthesis of neurosteroids such as pregnenolone and
Retinoic acids induce neurosteroid biosynthesis in human glial GI-1 Cells via the induction of steroidogenic genes.
Journal of biochemistry • 2009 |
secretion by both JEG-3 and BeWo cell lines were stimulated at high concentrations of
(1 x 10(-6], whereas progesterone secretion by JAR cells was not stimulated.”
Retinoic acid stimulates placental hormone secretion by choriocarcinoma cell lines in vitro.
Endocrinology • 1991 |
“Retinol significantly decreased both hormone levels, however
Testosterone and progesterone level alterations in the adult rat after retinoid (retinol or retinoic acid) treatment (imprinting) in neonatal or adolescent age.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme • 1998 |
“The antiproliferative effect of
may also be direct or indirect by virtue of down-regulation of the receptors for one of the mitogenic hormones, possibly
Interaction of retinoids with steroid and peptide hormones in modulating morphological and functional differentiation of normal rat mammary epithelial cells.
Endocrinology • 1995 |
“Results showed that both retinol and
production in this cloned cell line.”
An in vitro cell model system to study the action of retinoids on Leydig cell steroidogenesis.
Biochemistry international • 1990 |
“As compared to their respective controls, all concentrations of
and beta-carotene increased
content in the media.”
Comparative role of retinol, retinoic acid and beta-carotene on progesterone secretion by pig corpus luteum in vitro.
Journal of reproduction and fertility • 1988 |
and its accumulation in response to human low density lipoprotein were significantly higher in cells preincubated with
than in the control cells.”
“Surprisingly, the deleterious concentrations of
accumulation significantly higher than the medium control value.”
Lack of difference between retinoic acid and retinol in stimulating progesterone production by luteinizing granulosa cells in vitro.
Endocrinology • 1987 |
“Rates of secretion of
and 20alpha-hydroxypregn-4-en-3-one, both on days 9 and 15, were lower for the rats given
Studies on metabolism of vitamin A. The effect of vitamin A status on the secretion rates of some steroids into the ovarian venous blood of pregnant rats.
The Biochemical journal • 1971 |
“In addition, our results showed that both
treatments resulted in increased RARE and p53 gene activity.”
“Our studies also demonstrate that the potency of
on cell growth inhibition may be increased through combination of estrogen and
“The growth inhibitory effects of
were further increased in the presence of
, suggesting their effects are additive.”
“These inhibitions on telomerase activity by
were potentiated by co-treatment with
, and correlated well with their observed growth inhibitory effects.”
“We further demonstrated that p53 and p21 protein expression were induced following the
Activation of p53, inhibition of telomerase activity and induction of estrogen receptor beta are associated with the anti-growth effects of combination of ovarian hormones and retinoids in immortalized human mammary epithelial cells
Cancer Cell International • 2005 |
Help us improve
, we'd love to hear your feedback: