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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Progesterone
drug:
Thrombin Alfa
Research Papers that Mention the Interaction
“In study 2, in vitro treatment with r-hFSH, r-hLH , and hCG markedly increased (P < 0.05) VEGF and progesterone production by the NLGC in a dose- and time-dependent manner.”
Follicle-stimulating hormone and luteinizing hormone/chorionic gonadotropin stimulation of vascular endothelial growth factor production by macaque granulosa cells from pre- and periovulatory follicles.“Maintaining EGF at 20 ng/mL and varying rhMIS yielded significant reduction in EGF-mediated proliferation and progesterone production per cell at 2 and 20 ng/mL rhMIS.”
“The rhMIS decreased progesterone production per cell after 4 days exposure, but only in the higher doses.”
“These experiments demonstrate rhMIS inhibits basal and EGF-stimulated human granulosa-luteal cell proliferation and progesterone production.”
“In vitro, treatment with human recombinant NAMPT (100 ng/ml, 48 h) halved basal and IGF1-induced progesterone secretion, and this was associated with a reduction in STAR and HSD3B protein levels and MAPK3/1 phosphorylation levels in granulosa cells.”
Expression and effect of NAMPT (visfatin) on progesterone secretion in hen granulosa cells.“In cultured bovine granulosa cells, human recombinant CHEMERIN (hRec, 200 ng/ml) reduced production of both progesterone and estradiol, cholesterol content, STAR abundance, CYP19A1 and HMGCR proteins, and the phosphorylation levels of MAPK3/MAPK1 in the presence or absence of FSH (10−8 M) and IGF1 (10−8 M).”
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