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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Progesterone and Threonine

supplement:

Progesterone

supplement:

Threonine

Research Papers that Mention the Interaction

On the basis … that during progesterone treatment only … of glycine, threonine , cystine and serine were lower fasting and postprandially than they were fasting on control days, it has been suggested … of these four compounds, or a combination of several of them, may be critical in regulating peripheral protein catabolism.
Metabolism: clinical and experimental  •  1967  |  View Paper
In addition, replacement of Thr 60 by Ala reduces the affinity for progesterone by a factor of three.
The Journal of Steroid Biochemistry and Molecular Biology  •  1991  |  View Paper
In contrast, substitutions of the threonine residues of the C- or N-terminal moities had no effect, whereas the replacement of both threonines reduced the affinity for progesterone 2- to 3-fold.
Protein engineering  •  1995  |  View Paper