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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
supplement:
Threonine
Research Papers that Mention the Interaction
“On the basis … that during progesterone treatment only … of glycine, threonine , cystine and serine were lower fasting and postprandially than they were fasting on control days, it has been suggested … of these four compounds, or a combination of several of them, may be critical in regulating peripheral protein catabolism.”
The effect of progesterone on the concentration of plasma amino acids in man.“In addition, replacement of Thr 60 by Ala reduces the affinity for progesterone by a factor of three.”
Identification of residues essential for progesterone binding to uteroglobin by site-directed mutagenesis“In contrast, substitutions of the threonine residues of the C- or N-terminal moities had no effect, whereas the replacement of both threonines reduced the affinity for progesterone 2- to 3-fold.”
Progesterone binding to uteroglobin: two alternative orientations of the ligand.
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