supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Progesterone
drug:
Terbutaline
Research Papers that Mention the Interaction
“ Terbutaline (10(-6) M) increased 3 beta-HSD mRNA, 3 beta-HSD content and progesterone production (1.5- to 3-fold), an effect which could be prevented by alprenolol.”
Alterations in 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) mRNA accumulation induced by beta-adrenergic stimulation in cultured porcine granulosa cells.“The rate of progesterone secretion by the trophoblastic tissue was 47.5 +/- … (control) at 450 micrograms low density lipoprotein/mL. The rates of progesterone production and cAMP accumulation …, by 10(-5) M terbutaline , and the terbutaline effect was blocked by the …-1-naphthalenesulfonamide (W-7) or 50 microM trifluoperazine.”
“Cells from term human placentas were maintained in culture, and progesterone production was monitored over … 1-adrenergic receptor agonist dobutamine (10(-5) M) and the beta 2-adrenergic receptor agonist terbutaline (10(-… progesterone production by 36 +/- 19% and 49 +/- 8% (+/- SE), … that in controls (P less than 0.001).”
“Compared with the medium of matched controls, progesterone in medium increased 36 +/- 6% (mean +/- SE) when cells were treated with terbutaline and 38 +/- 7% when cells were treated with isoproterenol.”
“However, progesterone pretreatment set back the uterine action of terbutaline , increased the density of the beta2-adrenergic receptors and their mRNA level and increased the G-protein-activating property of terbutaline.”
Pregnancy-induced decrease in the relaxant effect of terbutaline in the late-pregnant rat myometrium: role of G-protein activation and progesterone.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback