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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
drug:
Spironolactone
Research Papers that Mention the Interaction
“Use of spironolactone was associated with changes in the result distribution of AMH, FSH, LH, and progesterone.”
Reproductive Endocrinology Reference Intervals for Transgender Women on Stable Hormone Therapy.“ Progesterone and 17alpha-hydeoxyprogesterone levels increased to a greater extent than LH and FSH in response to spironolactone , reflecting either adrenal or testicular enzyme inhibition.”
“ Spironolactone specifically blocked testosterone secretion and increased progesterone concentration without inducing cell mortality.”
Pig Leydig cell culture: a useful in vitro test for evaluating the testicular toxicity of compounds.“Abstract Spironolactone pretreatment protects the rat against the anesthetic effect of progesterone , desoxycorticosterone and hydroxydione sodium; it also prevents acute digitoxin poisoning.”
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