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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
supplement:
Sphingosine 1-Phosphate
Research Papers that Mention the Interaction
“In contrast, S1P at 1μM is able to antagonize the proliferation inhibitory effect of progesterone.”
Non-genomic rapid responses via progesterone in human peripheral T cells are not indirectly mimicked by sphingosine 1-phosphate“The administration of S1P also significantly decreased the percentage of luteal apoptotic cells induced by PGF‐2α.”
Local effects of the sphingosine 1‐phosphate on prostaglandin F2alpha‐induced luteolysis in the pregnant rat“Surprisingly, however, exogenous S1P inhibits agonist-stimulated progesterone in both cell types by inhibiting cyclic AMP accumulation, suggesting different mechanisms of action.”
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