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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Progesterone and Sirolimus



Research Papers that Mention the Interaction

Increased progesterone production in response to treatment with human chorionic gonadotropin or forskolin was also blocked by rapamycin pretreatment.
Endocrine  •  2016  |  View Paper
A twofold increase in S6 kinase activity occurred within 1 h of progesterone stimulation and rapamycin inhibited this activity.
Addition of rapamycin within 3 h, but not 6 h, of progesterone treatment inhibited GVBD.
General and comparative endocrinology  •  1999  |  View Paper
Rapamycin , an inhibitor of p70S6K activation, caused oocytes to undergo germinal vesicle breakdown earlier than control oocytes, and sensitivity to progesterone was increased.
Molecular and Cellular Biology  •  1999  |  View Paper