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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Progesterone and Recombinant Interferon Beta

Research Papers that Mention the Interaction

The administration of beta interferon as therapy of breast cancer seems to increase the estrogens and progesterone concentration in the neoplastic tissue and so it aims to improve the sensitivity to the tamoxifen treatment.
La Clinica terapeutica  •  1995  |  View Paper
Low … of beta-IFN (10 IU/ml of culture medium) produce … enhancement of ER in 60% and of PR in 42% of cases, while higher concentrations of beta-IFN (1000 IU/ml of culture medium) produce an enhancement of ER in 32%, and of PR in 82% of cases.
Our data suggest that beta-IFN could affect cellular hormone sensitivity through a modification of ER and PR and it can also determine a variation of PG output in human endometrial cancer.
Journal of steroid biochemistry  •  1988  |  View Paper