Possible Interaction: Progesterone and Recombinant Human Chorionic Gonadotropin

“Serum concentrations of FSH, estradiol and progesterone were significantly higher in the high-dose group at day 6 of rFSH treatment and on the day of HCG administration.”

“Plasma progesterone levels neared 10 ng/mL 19 hours after hCG administration, plateaued for 24 hours, and increased again thereafter.”

“ Progesterone but not PP14 levels were significantly higher and less variable after hCG than after saline administration on this day.”

“Concentrations of inhibin and progesterone are significantly higher in follicular fluids collected after ovulation induction with HCG compared with ovulation induction with GnRHa (P < 0.001, P < 0.02, respectively).”

“CONCLUSION Lu eal su pport with P increases the PR after hMG and hCG in duction.”

“Plasma progesterone increased significantly (P less than .001) above base line after hCG and placebo administration but this was not observed after hCG and alcohol administration.”

“It was concluded that, while hCG increased the magnitude and duration of the luteal P secretion, it did not clearly improve the pregnancy rate.”

“We hypothesized that administration of hCG to recipients at embryo transfer (ET) would induce accessory CL, increase serum progesterone concentrations, and reduce early embryonic loss (as measured by increased transfer pregnancy rates).”

“However, the association of nanoprogesterone with hCG causes the cellular death of initial follicles but shows efficacy in IVM.”

“ hCG stimulated the synthesis and secretion of progesterone and oestradiol, whereas ovarian steroidogenesis in the buserelin-treated group was comparable with that in the control group.”