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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
supplement:
Progesterone
drug:
Megestrol Acetate
Research Papers that Mention the Interaction
“Patients receiving nomegestrol acetate had a significantly higher incidence of regular progestogen-associated bleeding in comparison with those receiving medroxyprogesterone acetate or natural progesterone , and patients receiving dydrogesterone had a significantly higher incidence of regular progestogen-associated bleeding in comparison with those receiving natural progesterone. ”
Bleeding patterns during continuous estradiol with different sequential progestogens therapy“This antigonadotropic effect had an impact on ovarian function: in premenopausal women on nomegestrol acetate (n = 21), progesterone secretion was inhibited attesting to the absence of corpus luteum, the pre-ovulatory peak of estradiol was inhibited and plasma estradiol concentrations were decreased.”
“ Megestranol was found to increase the quantity of corpus luteum , while the combination of twice as much megestranol with spasmolitin did not have any effect on the corpus luteum.”
[Nature of the ovulation and the state of the preimplantation fetuses in the experimental administration of hormonal and neurotropic agents].“ Progesterone is a more effective inhibitor of mitochondrial respiration than the metabolically related steroids pregnenolone, pregnandione and allo -pregnanolone, and also than the artificial gestagens norprogesterone, 4-hydroxy-17α-acetoxyprogesterone , chlormadinone and 1-dehydrochlormadinone.”
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