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Last Updated: 8 months ago

Possible Interaction: Progesterone and Medroxyprogesterone Acetate

Research Papers that Mention the Interaction

CONCLUSIONS The … pr gesterone co uld inhibit the growth, promote apoptosis and inhibit metastasis of endometrial carcinoma, MIF could inhibit the growth and … more strongly inhibit the growth, promote apoptosis and inhibit metastasis of endometrial carcinoma than MIF or MPA , a nd synergistic effect was observed on …, PR, bax and bcl-2.
Zhonghua fu chan ke za zhi  •  2003  |  View Paper
The progesterone resistance is counteracted by progestins ( Medroxyprogesterone acetate , Dienogest, Danazol, Levonorgestrel) or by Selective progesterone receptor modulators, a class of drugs under development.
European journal of obstetrics, gynecology, and reproductive biology  •  2017  |  View Paper
Consequently, progesterone , the name of an individual hormone, should not be used as a synonym for MPA.
Climacteric : the journal of the International Menopause Society  •  2014  |  View Paper
The central hypothesis examined … this paper is that MPA more so than … concentrations of progesterone (P4) is likely to repress immune function at doses within the range found in the serum of … users due to its potent glucocorticoid-like immunosuppressive properties which could influence the pathogenicity of infectious diseases.
Endocrinology  •  2013  |  View Paper
In the presence of progesterone , progesterone receptor A (PRA) interacts with the G protein Gα13, while MPA drives PR to interact with tyrosine kinase c-Src and to activate phosphatidylinositol-3 kinase, leading to the activation of RhoA/ROCK-2.
PloS one  •  2008  |  View Paper
Overlapping in gene regulation by progesterone and MPA occurred, but the majority of genes regulated by these hormones were distinct.
Oncology reports  •  2008  |  View Paper
Combined treatment with two progestins was superior to single progestin treatment, with progesterone plus medroxyprogesterone acetate (MPA) achieving over 85% cell kill in both TRAIL‐sensitive and ‐resistant OCa cell lines.
Journal of cellular biochemistry  •  2007  |  View Paper
Progesterone inhibits the 21-hydroxylation of 17α-hydroxyprogesterone by human adrenal cortex microsomes.
Experientia  •  2005  |  View Paper
Consistent with the regulation by progesterone of the decidualization process in vivo, medroxy-progesterone acetate elevated the tissue factor content of primary stromal cell cultures 8-fold over basal values.
The Journal of clinical endocrinology and metabolism  •  1993  |  View Paper
The in vitro growth of cells derived … tumors after relapse under treatment with medroxyprogesterone acetate or tamoxifen was … enhanced by progesterone or tamoxifen (CAS: 10540-29-1) in concentrations corresponding to therapeutical serum levels and in accordance with in vivo resistance to the endocrine therapy applied before cell sampling.
Journal of the National Cancer Institute  •  1984  |  View Paper
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