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Last Updated: 8 months ago

Possible Interaction: Progesterone and Ghrelin

supplement:

Progesterone

drug:

Ghrelin

Research Papers that Mention the Interaction

Ghrelin was correlated negatively with HOMA-IR (P < 0.001), 17 OH progesterone (P = 0.05), total (P = 0.015) and free testosterone (P = 0.013).
Journal of pediatric and adolescent gynecology  •  2010  |  View Paper
All of the investigated ghrelin concentrations decreased progesterone (P(3)) but had no effect on human chorionic gonadotrophin (hCG) secretion.
Reproductive biology  •  2010  |  View Paper
Both basal and hCG-stimulated P release was significantly decreased by ghrelin , which was able to reduce PGE(2) and increase PGF(2alpha) luteal release.
The Journal of clinical endocrinology and metabolism  •  2007  |  View Paper
The mRNA and protein expression of ghrelin and GHS-R1a was significantly greater in mid- and late luteal phases.
Domestic animal endocrinology  •  2014  |  View Paper
Additions of FSH, IGF-I and ghrelin to culture medium reduced the release of progesterone and increased testosterone and estradiol output by fragments isolated from control animals.
Folia biologica  •  2014  |  View Paper
In conclusion, the presence of ghrelin and its receptor in porcine corpora lutea and the direct inhibitory effects of ghrelin on luteal P4 secretion and 3β-HSD suggest potential auto/paracrine regulation by ghrelin in the luteal phase of ovary function.
Theriogenology  •  2012  |  View Paper
Ghrelin promoted proliferation (PCNA, cyclin B1, MAPK) and progesterone secretion but suppressed apoptosis (Bax, caspase 3, p53).
Domestic animal endocrinology  •  2010  |  View Paper
Results demonstrated that Ghrelin60 increased progesterone concentration, reduced CC viability, induced CC DNA damage, and decreased blastocyst and hatching rate compared with C (P < 0.05).
Reproduction in domestic animals = Zuchthygiene  •  2021  |  View Paper