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Last Updated: 2 years ago

Possible Interaction: Progesterone and Genistein

supplement:

Progesterone

supplement:

Genistein

Research Papers that Mention the Interaction

Pretreatment with genistein (50 and 250 micromol/l) decreased capacitation-induced tyrosine phosphorylation and resulted in a loss of phosphorylation in response to progesterone treatment.
Molecular human reproduction  •  2002  |  View Paper
Furthermore, pre-incubation with the two tyrosine kinase inhibitors erbstatin and genistein inhibited the induction of acrosome reaction by progesterone and, partially, by PAF.
Molecular and Cellular Endocrinology  •  1995  |  View Paper
GEN also significantly increased progesterone and E2 levels in the serum of aged rats and reduced the levels of LH and FSH in the serum of both young and aged rats.
Polish journal of veterinary sciences  •  2019  |  View Paper
Supplementation of Genistein promoted the secretion of E2 and increased the expression of Star and Cyp19a1 mRNA, whereas suppressed the level of progesterone (P4) accompanied with a decline in the level of Hsd3b1 mRNA expression.
Cell biology international  •  2019  |  View Paper
We hypothesized that genistein can interfere with the regulation of uterine fluid volume, secretion rate and expression of aquaporin in the uterus by female sex‐steroids, i.e., estrogen and progesterone.
Environmental toxicology  •  2017  |  View Paper
Additionally, genistein (6.0 and 36μM) increases progesterone , testosterone, and dehydroepiandrosterone (DHEA) levels, but decreases estrone and estradiol levels.
Toxicology and applied pharmacology  •  2016  |  View Paper
…,genistein significantly … the progesterone- and ZP3-6 peptide-mediated induction of the acrosome reaction and led to a dose-dependent inhibition of sperm-zona pellucida binding; while … motility and capacitation were not affected by this phytoestrogen, as indicated by computer-assisted sperm motion analysis and the CTC assay, respectively.
Asian journal of andrology  •  2007  |  View Paper
Daidzein or genistein at non-toxic concentrations alone or combined with forskolin or pregnenolone significantly reduced progesterone synthesis.
Reproductive toxicology  •  2007  |  View Paper
Genistein at a dose of 45 microM inhibited Prl-stimulated progesterone secretion beneath the control level in theca and down to the control in luteal cells.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  1999  |  View Paper
Genistein … progesterone secretion by bovine and rabbit granulosa cells (at 0.01-10 microg/ml), estradiol output by rabbit granulosa cells (at 1 microg/ml) and … microg/ml), as well as cAMP production by bovine (at 0.001-1 microg/ml) and rabbit (at 1 microg/ml) granulosa cells.
The Journal of Steroid Biochemistry and Molecular Biology  •  1997  |  View Paper
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