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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Progesterone and Estrone Sulfate

Research Papers that Mention the Interaction

In contrast, gestagenes such as progesterone enhanced E3S uptake in a concentration-dependent manner to up to 300% of the control, accompanied by a significant decrease in the OATP2B1 Km value for E3S (control, Km = 14 μM; in the presence of 31.6 μM progesterone, Km = 3.6 μM).
Molecular Pharmacology  •  2006  |  View Paper
Progesterone provokes an important decrease in the uptake and in estradiol levels after incubation of [3H]estrone sulfate with the MCF-7 cells.
Journal of steroid biochemistry  •  1989  |  View Paper
These oestrogen sulphates also very significantly stimulated the number of progesterone specific binding sites, 7--10 times in relation to the non-treated animals.
Acta endocrinologica  •  1982  |  View Paper