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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Progesterone
drug:
Estrone Sulfate
Research Papers that Mention the Interaction
“In contrast, gestagenes such as progesterone enhanced E3S uptake in a concentration-dependent manner to up to 300% of the control, accompanied by a significant decrease in the OATP2B1 Km value for E3S (control, Km = 14 μM; in the presence of 31.6 μM progesterone, Km = 3.6 μM).”
Modification of OATP2B1-Mediated Transport by Steroid Hormones“ Progesterone provokes an important decrease in the uptake and in estradiol levels after incubation of [3H]estrone sulfate with the MCF-7 cells.”
“These oestrogen sulphates also very significantly stimulated the number of progesterone specific binding sites, 7--10 times in relation to the non-treated animals.”
Effects of seven different oestrogen sulphates on uterine growth and on progesterone receptor in the foetal uterus of guinea pig after administration to the mother.
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