Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Progesterone and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

CONCLUSION Pr gesterone en hanced the hematologic toxicity of dox orubicin wi thout altering its pharmacokinetics, suggesting that progesterone could modulate P-glycoprotein at the level of pluripotent hematopoietic stem cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  1993  |  View Paper
…)progesterone … doxorubicin and 5-fluorouracyl (drugs used in breast cancer treatment); 5) an association between breast cancer and HRT was suspected upon the addition of progestin …) the big resemblance among the breast cancers reported for POC and their similarity with breast malignancies diagnosed in pregnancy suggest the existence of.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz  •  2008  |  View Paper
In experiments with combined treatment of doxorubicin-sensitive MCF-7 and HeLa cells, progesterone in a concentration of 10(-7)M attenuated the cytostatic effect of doxorubicin (p<0.05), while 6alpha-methylpentarane in the studied concentrations did not modulate it.
Bulletin of experimental biology and medicine  •  2002  |  View Paper
Corticosterone (CT), progesterone (PG), and retinoic acid (RA) are capable of inhibiting Doxorubicin (Dox) from inducing apoptosis in rat cardiomyocytes.
Journal of biochemical and molecular toxicology  •  2016  |  View Paper
A similar twofold acceleration of doxorubicin flip-flop rate across membranes was observed with neutral mild detergents, including Tween 20, Nonidet P-40 and Triton X-100, and certain Pgp modulators, such as verapamil and progesterone.
European journal of biochemistry  •  1999  |  View Paper