supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Progesterone
drug:
Dexmedetomidine
Research Papers that Mention the Interaction
“The sedative effect of Dex was more significant in patients during the luteal phase than during the follicular phase.”
Influence of different menstrual phases on the Bispectral Index during dexmedetomidine sedation“Using the … demonstrated that DEX …, progesterone , and testosterone-mediated 5α-androstanediol formation at 1.5 μM. Further study demonstrated that DEX also directly inhibited rat testis cholesterol side … the expression of Cyp17a1 and Srd5a1, and increases ROS production, thus leading to lower production of androgens in immature Leydig cells.”
Effects of dexmedetomidine on the steroidogenesis of rat immature Leydig cells
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback