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Last Updated: 8 months ago

Possible Interaction: Progesterone and Dehydroepiandrosterone Sulfate

Research Papers that Mention the Interaction

Tsui et al.’s experiment lends support to the theory that circulating DHEA-S in women on supplementation may alter serum progesterone levels.
Journal of Assisted Reproduction and Genetics  •  2017  |  View Paper
DHEA-S to the pooled serum of … in a linear increase in progesterone levels on two of three commercially available immunoassays (p < 0.05).ConclusionsDHEA-S can interfere with standard progesterone … programs, and thus serum progesterone levels in IVF patients on DHEA supplementation may not reflect truly bioactive progesterone.
Journal of Assisted Reproduction and Genetics  •  2016  |  View Paper
Subsequent interaction studies indicated that progesterone only increases OATP2B1-mediated E(1)S and DHEAS transport, whereas uptake of BSP, atorvastatin and glibenclamide was either inhibited or not affected.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2012  |  View Paper
A positive correlation was found between circulating progesterone and DHEA-S levels (r = 0.50, p < 0.002 after adjustment for age).
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  2006  |  View Paper
The synthesis of dehydroepiandrosterone sulfate and the metabolism of progesterone , estrone, and estradiol are affected.
Akusherstvo i ginekologiia  •  1991  |  View Paper
The addition of DHA-sulfate and DHA inhibited 20 alpha-HSD activity for progesterone significantly, suggesting that the steroid produced by the feto-placental unit may be involved in the metabolism of progesterone in human placenta.
Endocrinologia japonica  •  1986  |  View Paper
The number of specific progesterone binding sites was increased 3.7-, 3.2-, and 2.0-fold by delta 5-diol, DHEA, and DHEAS , respectively.
Cancer research  •  1986  |  View Paper
DHA, DHA-S and 16-hydroxy-DHA stimulated oestrogen biosynthesis while high concentrations of DHA and DHA-S (but not 16-hydroxy-DHA) inhibited progesterone production.
Ciba Foundation symposium  •  1981  |  View Paper
In contrast, progesterone (PRGO) not only had no protective effect against the ischemic LTP impairment, but also attenuated the protective effect of DHEAS on the impaired LTP.
Neuropharmacology  •  2006  |  View Paper
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