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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
drug:
Cabergoline
Research Papers that Mention the Interaction
“Although all cabergoline treatments in this study were ineffective at preventing reproduction in coyotes, progressive inhibition of prolactin and progesterone with increasing dosages of cabergoline indicates that higher doses might be effective in preventing reproduction in coyotes.”
“Dosages of 1000 microg cabergoline decreased blood serum prolactin (P < or = 0.10) and progesterone (P < or = 0.06) concentrations, but apparently failed to decrease progesterone below the threshold necessary to maintain pregnancy in all but one animal.”
“However, progressive inhibition of prolactin and progesterone with increasing doses of cabergoline indicated that higher dosages might be effective in coyotes.”
Assessment of cabergoline as a reproductive inhibitor in coyotes (Canis latrans).“Cabergoline CG ), a dopamine agonist, and prolactin (PRL) added in vitro to isolated granulosa cells from immature rats cultured in serum-free medium inhibited FSH-stimulated production of progesterone.”
“In conclusion, CG inhibits FSH-stimulated progesterone and estradiol production by rat granulosa cells.”
“ Cabergoline decreased progesterone concentrations to < 1 ng ml-1 within 15-20 days.”
“ Cabergoline (Cab) , a dopamine agonist, inhibits the production and/or release of prolactin and reduces progesterone biosynthesis.”
“In conclusion, progesterone can neutralize the pregnancy preventing activity of Cab.”
Neutralization of pregnancy-preventing activity of cabergoline, a dopamine agonist with progesterone.
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