Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Progesterone and Ascorbate

supplement:

Progesterone

supplement:

Ascorbate

Research Papers that Mention the Interaction

“Combination of 0.4 or 0.8 mM AS with physiological LH concentrations significantly (P < 0.05) enhanced (up to 28%) PR production.”
“In experiment 2, levels of AS at 0.3 and 0.6 mM significantly increased (up to 29%) LH induced PR synthesis.”
Effect of ascorbate on luteinizing hormone stimulated progesterone biosynthesis in chicken granulosa cells in vitro.
Comparative biochemistry and physiology. Comparative physiology  •  1993  |  View Paper
“ Ascorbate (0.5 mM) enhanced the effect of 2-OH-E2 (but not E2) on progesterone production by 2-fold (p less than 0.05).”
Metabolism of [3H]2-hydroxyestradiol by cultured porcine granulosa cells: evidence for the presence of a catechol-O-methyltransferase pathway and a direct stimulatory effect of 2-methoxyestradiol on progesterone production.
Biology of reproduction  •  1987  |  View Paper