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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Progesterone
supplement:
Apigenin
Research Papers that Mention the Interaction
“In the presence of 100 nM of progesterone , 10 μM apigenin reduced PRE/Luc activity, indicative of mixed agonist activity.”
The Flavonoid Apigenin Is a Progesterone Receptor Modulator with In Vivo Activity in the Uterus“The agonistic effect of progesterone on SULT1E1 mRNA levels was concentration-dependently antagonized by RU486, UPA and ZK137316 as well as, with lower potency, apigenin.”
“Research findings indicated that apigenin causes significant decrease in estrogen, testosterone levels, LH and LH to FSH ratio, and significant increase in progesterone and FSH levels in serum of treated groups compared to PCOS control group.”
Therapeutic potentials of the natural plant flavonoid apigenin in polycystic ovary syndrome in rat model: via modulation of pro-inflammatory cytokines and antioxidant activity
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