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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Progesterone
drug:
Antipsychotic Agents
Research Papers that Mention the Interaction
“Furthermore, both preclinical and clinical studies show that certain treatments (antidepressants or antipsychotics ) may normalize the levels of PROG , suggesting that the amelioration of psychiatric symptoms may occur due to upregulation of PROG metabolites.”
Progesterone and its metabolites as therapeutic targets in psychiatric disorders“All APs used at their IC50s significantly inhibited progesterone (p=0.0022) and androstenedione (p=0.0027) production.”
Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells.“ Progesterone treatment alone, decreased the duration of catalepsy induced by the minor (1.0 mg/kg) neuroleptic dose.”
“In addition, the neuroleptic haloperidol (0.1 mg/kg) was shown to cause long lasting increases of progesterone levels.”
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