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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Progesterone and Anti-Anxiety Agents

Research Papers that Mention the Interaction

There is a dramatic potential for therapeutic anxiolytic activity of pharmacological compounds derived from powerful anxiolytic agents, such as the progesterone derivative, allopregnanolone.
Expert review of neurotherapeutics  •  2004  |  View Paper
Ovariectomy obviates these cyclic variations and systemic progesterone and/or estrogen replacement can enhance approach and anti-anxiety behavior.
Pharmacology Biochemistry and Behavior  •  2009  |  View Paper
While no anxiolytic activity could be detected in the plus maze, the highest dose of progesterone (90 mg/kg) exerted an inhibitory effect on the conditioned avoidance response.
Psychopharmacology  •  1999  |  View Paper