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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Procarbazine
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Hexamethylmelamine, pentamethylmelamine and procarbazine are anticancer drugs known to interfere with pyridoxal phosphate.”
Changes in serum copper and zinc during treatment with anticancer drugs interfering with pyridoxal phosphate.“It is shown that at the initiating stage of procarbazine carcinogenesis in F1 female mice the parenteral administration of nicotinamide or pyridoxine results in a significant decrease in the lung adenoma rate from 77% to 18 or 46%, respectively.”
“Summary Intraperitoneal injection of the antitumor agent, procarbazine (MIH), produced a rapid and prolonged fall in plasma levels of pyridoxal phosphate in mice.”
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