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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Procaine and Thiamine





Research Papers that Mention the Interaction

ECKERT1,2 reported that procaine and other local anaesthetics form pi-electron complexes with thiamine , and he suggested that such complexes in nerves might be responsible for local anaesthesia.
Nature  •  1969  |  View Paper
Thiamin chloride augments the anesthetic action of procaine hydrochloride.
Thiamin chloride vitamin B 1 ) detoxifies procaine hydrochloride when given intraspinally, intravenously or by infiltration.
American journal of surgery  •  1956  |  View Paper