supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Procaine
drug:
Tetrodotoxin
Research Papers that Mention the Interaction
“ TTX blocked nerve …, as did procaine ; however, the potency of TTX (EC50 = 3.3 +/- 0.8.10(-9), cm = 1.3 +/- 0.4.10(-8) mol/l) was … than that of procaine (EC50 = 1.6 +/- 0.2.10(-4), cm = 2.5 4/- 0.3.10(-4) mol/l).”
[The local anesthetic effect of tetrodotoxin on the natural spike activity of the depressor nerve in rabbits].“The combined effects of TTX and procaine , in concentrations which produced about 50% inhibition of dV/dTdep in N cells when given separately, were found to be intermediate between those predicted by two models which assume identical and independent sites of action, respectively.”
“ Tetrodotoxin also prevented the positive chronotropic effect of procaine.”
“3 Tetrodotoxin and the local anaesthetics, procaine and lignocaine, reversibly abolished the responses of strip and perfused preparations to transmural stimulation.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback