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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Procaine and Tetrodotoxin

supplement:

Procaine

Research Papers that Mention the Interaction

TTX blocked nerve …, as did procaine ; however, the potency of TTX (EC50 = 3.3 +/- 0.8.10(-9), cm = 1.3 +/- 0.4.10(-8) mol/l) was … than that of procaine (EC50 = 1.6 +/- 0.2.10(-4), cm = 2.5 4/- 0.3.10(-4) mol/l).
Regional-Anaesthesie  •  1989  |  View Paper
The combined effects of TTX and procaine , in concentrations which produced about 50% inhibition of dV/dTdep in N cells when given separately, were found to be intermediate between those predicted by two models which assume identical and independent sites of action, respectively.
Brain Research  •  1984  |  View Paper
Tetrodotoxin also prevented the positive chronotropic effect of procaine.
Japanese journal of pharmacology  •  1981  |  View Paper
3 Tetrodotoxin and the local anaesthetics, procaine and lignocaine, reversibly abolished the responses of strip and perfused preparations to transmural stimulation.
British journal of pharmacology  •  1978  |  View Paper