Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Procaine and Calcium Supplement



Research Papers that Mention the Interaction

Microelectrophoretic methods were also used to study the effect of PRHCL (8 × 10−4 and 8 × 10−2M) on RBC membrane calcium binding, with the results indicating that PRHCL competes with calcium for neuraminate binding sites.
Cell Biophysics  •  2008  |  View Paper
Procaine HCl was more efficient than PABA in inhibiting calcium uptake at equimolar concentrations.
Biochemical and biophysical research communications  •  1977  |  View Paper
procaine and tetracaine not only affect key steps of the Ca-… also exert an indirect effect on membrane permeability to calcium and suggest that the consequent myoplasmic calcium increase induced by the anesthetics might account …, such as sustained contraction and eventual rigidity of both fast-twitch and masticatory muscles.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2013  |  View Paper
Lower concentrations of tetracaine (0.5mm) and procaine (⩽10mm) blocked contractions due to caffeine (at pCa ⩾6.73), sulphydryl oxidizing agents, or Ca2+ -induced Ca2+ release (CICR).
Journal of Muscle Research & Cell Motility  •  2005  |  View Paper
Procaine (0.3mM) reversibly decreased the amplitude and the rate of rise of the calcium transient.
The Journal of physiology  •  1995  |  View Paper
The caffeine‐evoked intracellular calcium increase was reduced by two inhibitors of calcium‐induced calcium release, ryanodine and procaine.
The Journal of physiology  •  1992  |  View Paper
Procaine slowed down the rate of calcium uptake by SR vesicles without enhancing the vesicles' passive permeability.
European journal of biochemistry  •  1991  |  View Paper
Procaine (5 mM), which blocks release of calcium from intracellular stores, produced an effect on somatostatin secretion similar to that of BAPTA/AM.
The American journal of physiology  •  1990  |  View Paper
Procaine , on the other hand, caused a significant increase (P less than 0.01) in the unidirectional influx of calcium across the rat intestinal cells.
Comparative biochemistry and physiology. A, Comparative physiology  •  1988  |  View Paper
Furthermore, procaine inhibits the release of Ca from the store site, with no effect on the contractile protein.
Drugs under experimental and clinical research  •  1986  |  View Paper
Show More