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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Procainamide and Digitalis

supplement:

Digitalis

Research Papers that Mention the Interaction

This therapy may restore sinus rhythm, but conversion to sinus rhythm often requires the combined use of digitalis with a β-blocker or class I antiarrhythmic drug (quinidine, disopyramide, procainamide , propafenone, or flecainide).
Journal of cardiovascular pharmacology  •  1991  |  View Paper
Both diphenylhydantoin sodium and procaine amide can suppress digitalis arrhythmias due to enhanced automaticity, but procaine amide may promote “re-entry” arrhythmias by potentiating the intraventricular conduction defect caused by the glycoside.
Circulation  •  1967  |  View Paper
In three experiments, the ventricular tachycardia induced by digitalis was changed by procainamide to a slower, multifocal ventricular rhythm with widened complexes.
The American journal of cardiology  •  1967  |  View Paper