Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 9 months ago

Possible Interaction: Procainamide and Calcium Supplement

Research Papers that Mention the Interaction

We found that procainamide reduced intracellular calcium to steady-state levels in hearts in which left ventricular function completely recovered (developed pressure > 67% of the steady-state value).
American heart journal  •  1995  |  View Paper
Both the transient and the sustained hyperpolarization evoked in smooth muscle cells in the presence of procainamide (15 min) or quinidine in calcium-containing or in calcium-free solution, respectively, were inhibited.
European journal of pharmacology  •  1987  |  View Paper
Quinidine and procainamide prevented ouabain-induced increases of the Na content and the rate of Ca++ uptake as well as ouabain-induced toxicity.
The Journal of pharmacology and experimental therapeutics  •  1983  |  View Paper
Etafenone and procainamide increased Ca influx, while lidocaine had no effect on it.
Journal of cardiovascular pharmacology  •  1979  |  View Paper
Quinidine, but not procaine amide or lidocaine, decreased calcium uptake by both mitochondrial and microsomal fractions at different concentrations of calcium.
Canadian journal of physiology and pharmacology  •  1975  |  View Paper