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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Procainamide
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“We found that procainamide reduced intracellular calcium to steady-state levels in hearts in which left ventricular function completely recovered (developed pressure > 67% of the steady-state value).”
Role of intracellular calcium in the antiarrhythmic effect of procainamide during ventricular fibrillation in rat hearts.“Both the transient and the sustained hyperpolarization evoked in smooth muscle cells in the presence of procainamide (15 min) or quinidine in calcium-containing or in calcium-free solution, respectively, were inhibited.”
“Quinidine and procainamide prevented ouabain-induced increases of the Na content and the rate of Ca++ uptake as well as ouabain-induced toxicity.”
“Etafenone and procainamide increased Ca influx, while lidocaine had no effect on it.”
“Quinidine, but not procaine amide or lidocaine, decreased calcium uptake by both mitochondrial and microsomal fractions at different concentrations of calcium.”
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