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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Primidone and Folate

supplement:

Folate

Research Papers that Mention the Interaction

Abstract Phenobarbitone, diphenylhydantoin, and primidone reduce serum, red-blood-cell, and cerebrospinal-fluid folate levels in a high proportion of epileptic patients.
Lancet  •  1973  |  View Paper
The case of a patient who developed megaloblastic anemia caused by folate deficiency during treatment with primidone is reported.
Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma  •  1989  |  View Paper