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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Pregnenolone and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Since acute … of ACTH causes marked elevation of delta5-pregnene levels while patients with chronic ACTH excess (Cushing's disease and ectopic ACTH production) have normal levels, it is suggested that ACTH has a chronic influence on the intraadrenal utilization of delta5-pregnenes in addition to stimulating their formation.
The Journal of clinical endocrinology and metabolism  •  1977  |  View Paper