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Discover Supplement-Drug Interactions

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Possible Interaction: Prednimustine and Secretin



Research Papers that Mention the Interaction

The plasma secretin concentration in condition 1 was 0.8 pM; plateau concentration in condition 2 was 9.8 pM ; and integrated mean concentration in condition 3 was 4.8 pM. It is concluded that secretin at approximately physiologic plasma concentrations retards gastric emptying of solid food in humans.
Gastroenterology  •  1988  |  View Paper
Plasma secretin after 2 h of fat infusion was 17.7 +/- 1.8 pM and was greatly reduced by the presence of secretin antiserum.
Endocrinology  •  1991  |  View Paper
Secretin, … pM , caused a significant increase in juice flow (from 8.6 ± 1.6 to 30.7 ± 2.0 μl/20 min), protein output (from 227.….6 μg/20 min), but not in amylase output (from 247.9 ± 57.2 to 327.4 ± 80.6 Somogyi units/20 min).
Diabetes  •  1988  |  View Paper
Secretin inhibited gastrin release only at the maximal dose of 625 pM , when gastrin concentration in the venous effluent decreased from 93 +/- 19 to 68 +/- 19 pM after secretin.
Secretin significantly inhibited acid output to a minimum of 1.4 +/- 0.2 mumol/h at a concentration of 25 pM in the vascular perfusate (P less than 0.01).
Regulatory Peptides  •  1987  |  View Paper