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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Prazosin and Calcium Supplement

Research Papers that Mention the Interaction

Consistent with the results of our in-vivo experiments, both metoprolol and prazosin significantly inhibited the NE-induced SR Ca2+ leak and SCR.
PloS one  •  2015  |  View Paper
The results indicate that α1-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat, which is characterized by its sensitivity to blockade by prazosin and its relative insensitivity to antagonism by yohimbine or rauwolscine, can be subdivided into two distinct processes which are differentially influenced by blockade of calcium entry.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
The responses to noradrenaline in calcium-containing media were competitively inhibited by the alpha 1-selective antagonist, prazosin (pA2:9.23), and the responses to noradrenaline in calcium-free media were abolished by 10 nM prazosin.
European journal of pharmacology  •  1990  |  View Paper
Two calcium …, and prazosin produced a … the calcium accumulation when given prior to induction of ischemia (except for the highest dose of nicardipine), while they were ineffective when given … of reperfusion, and the suppression was found to be closely correlated with the decrease in HRxLVP before induction of ischemia.
Japanese journal of pharmacology  •  1987  |  View Paper
Pretreatment with the alpha-adrenergic blocking agents phentolamine or prazosin prevented the increase in total and intracellular calcium.
The Journal of clinical investigation  •  1983  |  View Paper