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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Praziquantel and Calcium Supplement

Research Papers that Mention the Interaction

The mode of action of PZQ involves increasing the calcium uptake of the parasite, resulting in tegumental damage and death of the parasite.
Antimicrobial Agents and Chemotherapy  •  2008  |  View Paper
The schistosomicidal activity of praziquantel (PZQ) is accompanied by a large influx of calcium into the worms, suggesting that this phenomenon could be the source of the observed muscular contraction, surface disruption and eventual death of the parasite.
Experimental parasitology  •  2008  |  View Paper
Praziquantel has a selective effect on the tegument of trematodes and increases permeability of calcium.
Veterinary journal  •  1997  |  View Paper
These results indicate that Ca 2 + may play an essential role in the contractile activity of the musculature caused by praziquantel , which is controlled to a certain degree by Mg 2+ .
Zhongguo yao li xue bao = Acta pharmacologica Sinica  •  1980  |  View Paper
Praziquantel leads to increase Ca 2 + influx and disrupts Ca 2+ homeostasis in adult Schistosoma .
Journal of Bioenergetics and Biomembranes  •  2020  |  View Paper