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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Povidone and Serum Albumin, Human

Research Papers that Mention the Interaction

Fluorescence spectroscopic studies revealed that HSA binds to the surface of PVP forming a protein corona.
However, SerCE and CE4 were released from BCMs in favor of binding to human serum albumin (HSA) while PVP prevented interaction with HSA.
Journal of controlled release : official journal of the Controlled Release Society  •  2019  |  View Paper
In accordance with previous studies on frozen aqueous solutions of PVP, the results suggest that unfrozen water dominated the dielectric response, with the local environment surrounding the HSA being strongly influenced by the PVP.
MTDSC data indicated that the PVP and HSA interact in a complex manner in solution, with a glass transition attributable to PVP being seen only in those systems where PVP was present in sufficient excess.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V  •  2004  |  View Paper