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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Potassium and Valproic Acid

supplement:

Potassium

Research Papers that Mention the Interaction

It is suggested that the extrasynaptic effects on potassium currents markedly contribute to the antiepileptic and antimanic effects of VPA.
European Neuropsychopharmacology  •  1993  |  View Paper
Typically, 2.4 mM (400 mg/L) valproate reduced the sodium current 54% and the potassium current 26%, at a membrane potential of 5 mV. Valproate did not affect the leakage conductance.
Epilepsia  •  1986  |  View Paper