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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Potassium and Valproic Acid



Research Papers that Mention the Interaction

It is suggested that the extrasynaptic effects on potassium currents markedly contribute to the antiepileptic and antimanic effects of VPA.
European Neuropsychopharmacology  •  1993  |  View Paper
Typically, 2.4 mM (400 mg/L) valproate reduced the sodium current 54% and the potassium current 26%, at a membrane potential of 5 mV. Valproate did not affect the leakage conductance.
Epilepsia  •  1986  |  View Paper