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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Potassium
drug:
Valproic Acid
Research Papers that Mention the Interaction
“It is suggested that the extrasynaptic effects on potassium currents markedly contribute to the antiepileptic and antimanic effects of VPA.”
Effects of valproate on early and late potassium currents of single neurons“Typically, 2.4 mM (400 mg/L) valproate reduced the sodium current 54% and the potassium current 26%, at a membrane potential of 5 mV. Valproate did not affect the leakage conductance.”
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