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Last Updated: 8 months ago

Possible Interaction: Potassium and Tubocurarine

supplement:

Potassium

supplement:

Tubocurarine

Research Papers that Mention the Interaction

The mechanism for this is unknown but it is probable that tubocurarine stabilises muscle cell membrane and thereby prevents potassium loss into the plasma.s Poulsen & Secher6 have demonstrated the peripheral neuromuscular blocking action of diethyl ether, an action similar to that of tubocurarine.
Anaesthesia  •  1974  |  View Paper
The ED50 of d-tubocurarine was found to fall as the potassium level was lowered by dietary restriction.
Anesthesiology  •  1982  |  View Paper
Potassium concentration gradients between the intracellular and the extracellular compartments may be more important than cellular potassium depletion per se in affecting responses to neuromuscular blocking agents such as succinylcholine, d-tubocurarine , or pancuronium.
Anesthesia and analgesia  •  1978  |  View Paper
The rate at which potassium ions antagonized the neuromuscular block produced by tubocurarine has been examined in isolated rat diaphragm muscle preparations.
British journal of pharmacology and chemotherapy  •  1961  |  View Paper