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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Potassium and Trimethoprim



Research Papers that Mention the Interaction

Compared with the control group, trimethoprim decreased potassium excretion by 572 nmol/min (CI, 299 to 845 nmol/min).
Figure 3 shows that 1 mmol/L of trimethoprim inhibited net potassium secretion by 59% (CI, 26% to 92%).
Annals of Internal Medicine  •  1993  |  View Paper
CONCLUSIONS Tr methoprim in creases plasma pot assium co ncentration probably by reducing urinary potassium excretion.
Clinical nephrology  •  2001  |  View Paper
Trimethoprim , but not sulfamethoxazole, was found to inhibit potassium secretion when perfused into distal tubules.
American journal of kidney diseases : the official journal of the National Kidney Foundation  •  1997  |  View Paper
In vivo, trimethoprim caused a > 50% reduction in potassium (K+) excretion due primarily to a fall in the [K+] in the lumen of the terminal CCD.
Kidney international  •  1996  |  View Paper